Active Ingredients: Norfloxacin
Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients.
Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
Fluoroquinoline treatment is associated with risk that is similar to or less than that associated with broad spectrum cephalosporins.
Therefore, cyclosporine serum levels should be monitored and appropriate cyclosporine dosage adjustments made when these drugs are used concomitantly. Medications Some quinolones exert an inhibitory effect on the cytochrome P-450 system, thereby reducing theophylline clearance and increasing theophylline blood levels.
Additionally other fluoroquinolones, especially enoxacin, and to a lesser extent ciprofloxacin and pefloxacin, also inhibit the metabolic clearance of theophylline.
As such, these drug interactions involving the fluoroquinolones appear to be drug specific rather than a class effect. The fluoroquinolones have also been shown to interfere with the metabolism of caffeine and the absorption of levothyroxine.
Sampling technique and sample size Since only 87 patient medical cards were fulfilled the inclusion criteria, all cards were included in the study. Data quality control Pre testing of the data collection format was undertaken at surgical ward of HFSUH before the actual data collection and completeness of collected data was checked each time.
Data analysis The collected data was clean and checked for its completeness, categorized, and analyzed using SPSS version 16.
Ethical consideration Before beginning data collection, official permission letter was obtained from school of pharmacy, Haramaya University.
After getting consent from the responsible bodies, patients chart were accessed using their card numbers and the confidentiality of data collected was maintained.
Name and address of the patient and prescriber is omitted from the data collection format. You will find a full list in the manufacturer's information leaflet supplied with your medicine.Treatment duration ranged from a required tract infections in men with and without identifiable urologic complications. Norfloxacin in the treatment of urinary minimum of seven days to a maximum of 30 days.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common norfloxacin side-effects What can I do if I experience this? Feeling sick nausea or being sick vomiting, indigestion, tummy abdominal pain Stick to simple foods - avoid rich or spicy meals Diarrhoea Drink plenty of water to replace lost fluids.
If the diarrhoea is severe or continues to be a problem, speak with your pharmacist or doctor for advice Headache Drink plenty of water and ask your pharmacist to recommend a suitable painkiller.
If the headaches continue, let your doctor know Feeling dizzy Do not drive and do not use tools or machines until you feel well again Rash If this is severe, let your doctor know Important: there are also a number of less common but more serious side-effects which have been associated with norfloxacin.
Speak with your doctor as soon as possible if you experience the following: An allergic-type reaction, such as swelling around your face or mouth, a skin rash, or any difficulty breathing. Pain or swelling in your joints.